These primer pairs are anticipated to make PCR products of specific lengths for the Pink1 wildtype allele, and correspondingly shorter PCR goods if alternatively spliced mutant Pink1 transcripts are current in cells (Fig. 3A)
Transcriptional profiling information counsel that Pink1 deletion might result in neuroinflammation and axonal problems, which are compensated for by particular modifications in gene expression. While these alterations may possibly in…