Anti-h PSA 8312 SPRN-5 | Medix Biochemica

Further Specification :
| Form/Appearance： Liquid, may turn slightly opaque during storage | Concentration： 5.0 mg/ml (+/- 10 %) | Notes： Clone 8312 reacts with non-reduced and reduced intact PSA as well as with reduced PSA fragments (Rye et al., 1999). In the same study affinities for free-PSA and PSA-ACT-complex were, 7.5 x 10-9 mol/l and 1.03 x 10-10, respectively. They also noted that antibodies binding to epitope group 6 form a good pair with antibodies from groups 1 and 3. Clone 8312 crossreacts with human kallikrein-2 (Rye, 1999a). Clone 8312 was coded as 5E4 in Rye et al. (1999). | Isotype： IgG1 | Clonality： Monoclonal | Epitope： Residues 3–11, group 6a as described in Rye et al. (1999) | Purity： ≥ 95 % | Affinity constant： KA= 3 x 109 1/M | Associated Products： Native PSA antigen, Lee Biosolutions 497-11 and 497-17, and native PSA-ACT complex, Lee Biosolutions 498-11 | Buffer： 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative | IEF Profile： 6.3–7.0 | Cross Reactivity： PSA/α1-ACT complex 15 %. Does not recognize human kallikrein-2 or PAP. | Specificity： Antibody recognizes human prostate-specific antigen