Anti-h PSA 8311 SPRN-1 | Medix Biochemica

Further Specification :
| Form/Appearance： Liquid, may turn slightly opaque during storage | Concentration： 1.0–1.1 mg/ml | Notes： Clone 8311 reacts with non-reduced and reduced intact PSA but not with reduced PSA fragments (Rye et al., 1999). In the same study affinities for free-PSA and PSA-ACT-complex were, 1.7 x 10-10 mol/l and 1.55 x 10-10, respectively. They also noted that antibodies binding to epitope group 6 form a good pair with antibodies from groups 1 and 3. Clone 8311 crossreacts with human kallikrein-2 (Black, 1999b) and can be used to develop a hK2-assay. | Isotype： IgG2a | Clonality： Monoclonal | Epitope： Residues 3–11, group 6a as described in Rye et al. (1999) | Purity： ≥ 95 % | Affinity constant： KA= 1 x 1010 1/M | Associated Products： Native PSA antigen, Lee Biosolutions 497-11 and 497-17 | Buffer： 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative | IEF Profile： 6.8–7.5 | Cross Reactivity： PSA/α1-ACT complex 76 %, Kallikrein | Specificity： Antibody recognizes human prostate-specific antigen