Anti-h PSA 8301 SPRN-5 | Medix Biochemica

Further Specification :
| Form/Appearance： Liquid, may turn slightly opaque during storage | Concentration： 5.0 mg/ml (+/- 10 %) | Notes： Clone 8301 reacts with non-reduced and reduced intact PSA but not with reduced PSA fragments (Rye et al., 1999). In the same study affinities for free-PSA and PSA-ACT-complex were, 9.0 x 10-9 mol/l and 5.2 x 10-9, respectively. They also noted that antibodies binding to epitope group 3a form a good pair with antibodies from groups 1, 5a, 5c and 6. Clone 8301 does not cross-react with human kallikrein-2 (Black, 1999b). | Isotype： IgG1 | Clonality： Monoclonal | Epitope： Residues 158–163, group 3 as described in Rye et al. (1999) | Purity： ≥ 95 % | Affinity constant： KA= 1 x 1011 1/M | Associated Products： Native PSA antigen, Lee Biosolutions 497-11 and 497-17 | Buffer： 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative | IEF Profile： 6.5–7.2 | Cross Reactivity： PSA/α1-ACT complex 59 %, Kallikrein | Specificity： Antibody recognizes human prostate-specific antigen