N. A different query is, if and how modifications in functionality of one particular channelHofmann et al. eLife 2018;7:e39300. DOI: https://doi.org/10.7554/eLife.12 ofResearch articleHuman Biology and Medicine Neurosciencefamily may influence other…
Ressing Piezo1 with mutations inside the hydrophobic cluster in the inner helix (n = 82 cells). Ehold = 0 mV. p0.001; NS, not significant, p0.05, one-way ANOVA with Dunnet's correction.…
Is may underlie Gb3 connected cellular stress and apoptosis as shown for instance in cardiomyocytes (Chimenti et al., 2015), peripheral blood mononuclear cells (De Francesco et al., 2011) or endothelial…
Y Magic Red Cathepsin L assay kit (Immunochemistry Technologies) and Lysosomal sulfatase assay kit (Marker Gene) have been made use of. The experiment was performed making use of the manufacture's…
Tps://doi.org/10.7554/eLife.16 ofResearch articleHuman Biology and Medicine NeuroscienceTo stay clear of burn lesions, a stimulus cut-off time of 16 s was set. Every single hind paw was tested three occasions (at…
Arch funds with the Interdisciplinary Center for Clinical Analysis (Interdisziplinares Zentrum fur Klinische Forschung, IZKF) in the University of Wurzburg, Germany (NU, EW: N-260). NU was supported by the German…
Expression: n = two male, n = four female; protein expression: n = 3 male, n = 1 female), old (!12 months; gene expression: n = 4 male, n =…