Ic L. Garland, PhD University of UtahAbstractObjective–This pilot randomized controlled trial purchase Lurbinectedin evaluated a novel trauma-informed model of Mindfulness Based Stress Reduction (TI-MBSR) as a phase-I trauma intervention for female survivors of interpersonal violence (IPV). Method–A community-based sample of women (Mean Age = 41.5, SD = 14.6) with a history of IPV were randomly assigned to an 8-week TI-MBSR intervention (n = 23) or a wait-list control group (n = 22). Symptoms of PTSD and depression, as well as anxious and avoidant attachment, were assessed pre- and post-intervention. Results–Relative to the control group, participation in TI-MBSR was associated with statistically and clinically significant decreases in PTSD and depressive symptoms, as well as significant reductions in anxious attachment. Retention in the intervention was high, with most participants completing at least 5 of the 8 sessions for the intervention. Minutes of mindfulness practice per week significantly predicted reductions in PTSD symptoms. Conclusion–TI-MBSR appears to be a promising and feasible phase I intervention for female survivors of interpersonal trauma. Keywords MBSR; mindfulness; interpersonal violence; trauma; post-traumatic stress disorder; Stage I RCT Interpersonal violence (IPV) can have lasting adverse effects across the lifespan on both mental and physical health outcomes (Felitti et al., 1998), as well as on relationships (Pearlman Saakvitne, 1995). Here we define IPV as the intentional use of physical or sexual violence against another person within the context of a relationship. This includes physical or sexual violence committed by a family member, intimate partner, friend, or acquaintance. In the U.S. at least one in three women have experienced episodes of IPV, including sexual assault and physical violence, in their lifetime, and most female survivors of IPV experience violence for the first time before the age of 25 (Black et al., 2011). TheCorresponding author: Amber Kelly, 275 Mount Carmel Ave, Hamden, CT 06518, [email protected], 203-582-7843.Kelly and GarlandPageconsequences of IPV can be lifelong and far reaching. For example, in one of the largest scale, population-level assessments of IPV, adult survivors of IPV lost SF 1101 chemical information approximately 8 million days of paid work in 2003 as a consequence of episodes of violence (Centers for Disease Control and Prevention, 2003). At least 30 of female survivors answering a survey through the National Institute on Injury Prevention reported psychological impacts from past violence, including symptoms of post-traumatic stress-disorder (PTSD) or depression, as well as increased needs for health care, housing services, and legal services (Black et al., 2011). Epidemiologic data indicate that women tend to experience a higher incidence of lifetime IPV than men as well as experience a higher incidence of revictimization (Lilly Valdez, 2012; Tang Freyd, 2012), gender differences which have been found consistently across varying socioeconomic strata, geographic locations, and cultures (Tang Freyd, 2012). Recurrent experiences of IPV may be one reason among many why women have twice the rate of PTSD as men (Iverson, et al., 2013, Kessler et al., 1995, 2005), exhibit PTSD symptoms for four times as long as men, report significantly poorer quality of life, and develop more comorbid psychiatric disorders (Breslau et al., 1998; Holbrook, Hoyt, Stein, Sieber, 2001; Institute of Medicine, 2012; S.Ic L. Garland, PhD University of UtahAbstractObjective–This pilot randomized controlled trial evaluated a novel trauma-informed model of Mindfulness Based Stress Reduction (TI-MBSR) as a phase-I trauma intervention for female survivors of interpersonal violence (IPV). Method–A community-based sample of women (Mean Age = 41.5, SD = 14.6) with a history of IPV were randomly assigned to an 8-week TI-MBSR intervention (n = 23) or a wait-list control group (n = 22). Symptoms of PTSD and depression, as well as anxious and avoidant attachment, were assessed pre- and post-intervention. Results–Relative to the control group, participation in TI-MBSR was associated with statistically and clinically significant decreases in PTSD and depressive symptoms, as well as significant reductions in anxious attachment. Retention in the intervention was high, with most participants completing at least 5 of the 8 sessions for the intervention. Minutes of mindfulness practice per week significantly predicted reductions in PTSD symptoms. Conclusion–TI-MBSR appears to be a promising and feasible phase I intervention for female survivors of interpersonal trauma. Keywords MBSR; mindfulness; interpersonal violence; trauma; post-traumatic stress disorder; Stage I RCT Interpersonal violence (IPV) can have lasting adverse effects across the lifespan on both mental and physical health outcomes (Felitti et al., 1998), as well as on relationships (Pearlman Saakvitne, 1995). Here we define IPV as the intentional use of physical or sexual violence against another person within the context of a relationship. This includes physical or sexual violence committed by a family member, intimate partner, friend, or acquaintance. In the U.S. at least one in three women have experienced episodes of IPV, including sexual assault and physical violence, in their lifetime, and most female survivors of IPV experience violence for the first time before the age of 25 (Black et al., 2011). TheCorresponding author: Amber Kelly, 275 Mount Carmel Ave, Hamden, CT 06518, [email protected], 203-582-7843.Kelly and GarlandPageconsequences of IPV can be lifelong and far reaching. For example, in one of the largest scale, population-level assessments of IPV, adult survivors of IPV lost approximately 8 million days of paid work in 2003 as a consequence of episodes of violence (Centers for Disease Control and Prevention, 2003). At least 30 of female survivors answering a survey through the National Institute on Injury Prevention reported psychological impacts from past violence, including symptoms of post-traumatic stress-disorder (PTSD) or depression, as well as increased needs for health care, housing services, and legal services (Black et al., 2011). Epidemiologic data indicate that women tend to experience a higher incidence of lifetime IPV than men as well as experience a higher incidence of revictimization (Lilly Valdez, 2012; Tang Freyd, 2012), gender differences which have been found consistently across varying socioeconomic strata, geographic locations, and cultures (Tang Freyd, 2012). Recurrent experiences of IPV may be one reason among many why women have twice the rate of PTSD as men (Iverson, et al., 2013, Kessler et al., 1995, 2005), exhibit PTSD symptoms for four times as long as men, report significantly poorer quality of life, and develop more comorbid psychiatric disorders (Breslau et al., 1998; Holbrook, Hoyt, Stein, Sieber, 2001; Institute of Medicine, 2012; S.