SPINT1/Hai1 is typically present in massive (e.g., ,ten-fold) extra over ST14/matriptase, which is consistent with swift inhibition of matriptase
ST14/matriptase and PRSS8/prostasin are needed for terminal differentiation of epithelia . Jointly with their inhibitor, SPINT1/Hai1, they maintain the structural and useful integrity of epithelia . All three proteins are…